Today's motor vehicles are complex mechatronic systems. On the other hand, there are trends in production, such as Industry4.0. These trends also have an impact on automotive final assembly, where new product and production technologiesmeet. Particularly in the case of safety-critical mechatronic functions, such as driver assistance systems, new requirementsare being added to the end-of-line commissioning. Only safe vehicles may leave production and be sent ontothe road. The commissioning of the new functions in the interaction between mechanics, electronics and informationtechnology, leads to increased expenditure, which results in long process times, parallel processes and high investmentcosts for measuring equipment. In order to reduce the end-of-line effort, the aim is to move commissioning to the assemblyline or to the supplier. On the one hand, this requires new process technologies, and on the other hand new methodsfor safeguarding commissioning concepts. Two possible approaches are presented in this paper.